a tool for identifying drug-targetable redox-active disulphides

Cathelicidin-4

Intramolecular

Cysteine 2 and cysteine 14

A redox-regulated disulphide may form within Cathelicidin-4 between cysteines 2 and 14.

Details

Redox score ?

nan

PDB code

Structure name

structure of a cyclic indolicidin peptide derivative with higher charge

Structure deposition date

2003-09-04

Thiol separation (Å)

2

Half-sphere exposure sum ?

19

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

2

Residue number B

14

Peptide name

Cathelicidin-4

Ligandability

Cysteine 2 of Cathelicidin-4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 14 of Cathelicidin-4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2 in protein A could not be asigned to a Uniprot residue.

Cysteine 14 in protein B could not be asigned to a Uniprot residue.

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